Biotin Side Effects

Reviewed by Terri Forehand RN
Biotin-rich foods, egg and whole grains

Vitamin B7 -- more commonly known as biotin (and occasionally vitamin H) -- is required for healthy skin, hair sweat glands, nerve tissue, bone marrow and nails. Biotin also aids in cell growth; metabolizing fats, carbohydrates and proteins into fuel for your muscles; and it helps your body make use of the other B-complex vitamins. While your body can't manufacture biotin on its own, deficiencies are rare, notes MedScape. So are side effects.

Potential Side Effects

There are potential side effects of biotine, either related to intake or deficiency.

Intake-Related

Biotin is considered non-toxic. It is a water-soluble vitamin -- in other words, your body can't store it and any excess is flushed from the body in urine. Side effects from excessive biotin intake are so rare that many reputable sources, including the University of Maryland Medical Center, report that they don't exist at all. There are, however, a very few documented cases of adverse affects from biotin intake:

  1. Unsubstantiated reports indicate that excess biotin intake may cause a noticeable increase in the need to urinate, or an unusual amount of sweating.
  2. University of Maryland Medical Center reports biotin is recommended for strengthening hair and nails; so it's little surprise that faster growth of your hair and nails may be a consequence of biotin use.
  3. The University of Washington Medical Center notes that some biotin users "may have side effects such as mild nausea, stomach cramping, or diarrhea."
  4. The Linus Pauling Institute of Oregon State University reports one case of "life-threatening eosinophilic pleuropericardial effusion in an elderly woman who took a combination of 10,000 mcg/day of biotin and 300 mg/day of pantothenic acid for two months." It's unclear whether the condition was caused by the combination of the two vitamins or another factor entirely.
  5. The National Institutes of Health lists biotin as "POSSIBLY SAFE when used in recommended amounts during pregnancy and breast-feeding," and lists no known side effects when taken with herbs or supplements.

Deficiency-Related

Even though biotin deficiency is rare, biotin levels may be affected by some medications, particularly long-term use of antibiotics and some anticonvulsants according to Oregon State University. Additionally, unlikely as it is, if you were to consume large amounts of raw egg whites, the National Institutes of Health (NIH) warns that you might become biotin deficient. This is because raw egg whites contain a glycoprotein that binds biotin and prevents its absorption.

In the unlikely event of a biotin deficiency, symptoms may include:

  • Scaly red rash on the face or around the genitals
  • Neurological problems such as depression, lethargy, numbness and tingling of the extremities

Biotin Recommendations

Because adverse affects from biotin are so rarely reported, there is no recommended maximum limit on biotin intake. Lack of biotin is very rare too, so there is no official RDA (Recommended Daily Allowance) issued for this vitamin. The NIH notes that the following amounts represent adequate intake of biotin:

  • Infants 0 - 12 months: 7 micrograms per day (mcg/day)
  • 1 to 3 years old: 8 mcg/day
  • 4 to 8 years old: 12 mcg/day
  • 9 to 13 years old: 20 mcg/day
  • 14 to 18 years old: 25 mcg/day
  • 18 and over, pregnant women: 30 mcg/day
  • Breastfeeding women: 35 mcg/day

In most cases a balanced diet will provide at least this amount of biotin, as will most daily multivitamins. Dietary sources of biotin include whole grains, egg yolks, organ meats, saltwater fish, poultry, legumes, pork, and yeast.

Seek Medical Help for Problems

With any type of nutritional supplements, or any other medicine for that matter, if you are experiencing any side effects you should let your healthcare provider know immediately. The signs may be easily recognizable and could be a combination of several factors, but if something simply does not feel right don't take a chance. What you are experiencing may not be a side effect of biotin specifically, but your doctor should be able to correctly diagnose the problem and then take the needed steps to correct and treat it.

Biotin Side Effects